is a multi-activity feed enzyme formulated specially for poultry, swine, ruminant and aqua feeds to enable better nutrient utilisation from feed. Resulting in more high quality meat, eggs or milk with lower total costs.

Natuzyme contains xylanase, b-glucanase, mannanase, alpha-amylase, phytase and other enzymes. The enzymes have a wide pH range, long-term stability and good thermostability, combining with high levels of enzyme activity to allow Natuzyme to be successfully applied to animal feeds with excellent results under wide ranging conditions around the world.

Many plant based feeds contain substrates with Anti-Nutritional Factors (ANFs), which include a variety of fibres or Non-Starch Polysaccharides (NSP), proteins, starches and phytate, which reduce animal growth.

Description of enzyme activities:

Natuzyme's originality lies

in the fact that all its six components work with high activity against a background of non-antagonistic, but, on the contrary, synergistic interaction of components among themselves. As a result, the drug becomes universal in terms of the composition of a complex diet, which simultaneously includes the grain components of all known traditional and non-traditional crops and the most diverse protein additives (oilcake, meal, bran, dry bard, dry beet, etc.).

The second originality of Natuzyme is

The presence in it of both microbial and fungal enzymes. Fungal enzymes Natuzyme cleave cellulose, β-glucans and xylans, and microbial proteins - proteins, starch, fiber, xylans and β-glucans. Consequently, for such groups of nutrients as cellulose, xylans and β-glucans, both fungal and microbial enzymes of Natuzyme act simultaneously.

The presence of phytase

in the list of activities completes the picture of complex hydrolytic processing of biopolymers of feed, resulting in the formation of the maximum amount of cleavage products that are digestible for the organism of animals and poultry.

Natuzyme is characterized simultaneously by high cyto-, amylo- and proteolytic activity in combination with phytase activity, which distinguishes it from all known multi-enzyme feed additives

Dynamics of energy and protein nutrition of rations in connection with Natuzyme application

Natuzyme enzymes improve the digestibility of this ANFs by smashing them down and make them digested, which leads to improved feed conversion.

Due to the splitting of non-starch polysaccharides and phytates under the action of Natuzyme, an additional amount of exchange energy is released:

Increase in exchange energy

This effect of adding exchange energy can be fully taken into account when characterizing the energy supply of these feed components.

Accessibility of mineral substances of the main fodders in connection with the inclusion in the Natuzyme diet

Phytase in Natuzyme has the most significant effect on the availability of minerals found in the main dietary feed. Her The action is aimed at breaking the phytic bonds between phosphorus and phytate or any other phosphorus-containing biopolymer.

As a result of effective work of phytase

phosphate ions are formed, which can be effectively absorbed into the blood in the small intestine. In addition, such an enzymatic reaction significantly improves the availability of other chemical elements and amino acids that were previously associated in the chain of phytic compounds. Thus, not one but a whole chain of enzymatic reactions is performed, making calcium, iron, zinc and amino acids of food proteins more accessible. That is why phytase should be considered not only as a factor of increasing the availability of phosphorus, but also as a means of increasing the availability of other macro- and microelements.

Excellent heat and temperature stability up to 90°C during pelleting.

Storage stability/ Shelf life

If stored dry at room temperature < 25°C the activity will not decrease below 90% of the declared activities within two years from the date of manufacture
Keep well closed, cool (room temperature) and dry.

Stability of activities (in% of baseline) of protease, cellulase, amylase and phytase at different heat treatment temperatures (65º, 75º, 85º, 90º С)

The figure shows that even at a heating temperature of 90ºС, the activity of the Natuzyme protease remains at 95%, cellulase at 80%, amylase at 90% and phytase at 91%. Such losses of activity are insignificant from the point of view of maintaining high effectiveness of the drug in animal and poultry diets.